Chemical AchieversAn online publication of Chemical Heritage Foundation

Pharmaceuticals and the Path to Biomolecules: Yams, Soybeans, and Pharmaceuticals: Starch Digestion by Amylase

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Lesson Overview
This activity will make students familiar with the most basic biochemicals found in the tubers of yams. Besides being a basic food, the yam has been the source of starting chemicals related to steroids since the 1930s. Students will identify qualitatively two major categories of organic molecules: starches and sugars. They will also chemically convert the starch to sugars and identify the conversion

Student Ability Level and Grouping
This lab is suitable for both average and above-average chemistry students. Ideally, students should work in groups of 3 or 4 but no more than that.

Expected Student Background and Skills
Before carrying out the activity, students should

  • be able to accurately measure reactants used in the activity and skillfully manipulate basic lab equipment;
  • have a conceptual understanding of basic molecular structure and bonding in organic molecules;
  • be familiar with metric units of measurement; and
  • have a conceptual and mathematical understanding of Dalton’s law of partial pressures.

Time and Materials Required
A minimum of one 45-minute period is needed to set up equipment, measure chemicals, and start the test-tube reactions. Another class period is needed to finish collecting data, exchange data with classmates, and discuss results.

Consumables

  • Starch solution
  • Lugol’s solution
  • Benedict’s solution

Non-consumables

  • 25-mL graduated cylinder
  • Metric ruler
  • Marking pens or pencils
  • Test tube (18 x 150 mm)
  • Test-tube rack
  • 250-mL beaker
  • Source of boiling water
  • Thermometer

Learning Objectives
After completing this activity, students should understand

  • basic laboratory techniques for identifying specific organic molecules;
  • the basic chemistry behind the conversion of one molecule to a different one and be able to identify it;
  • the structural changes that occur in the conversion of starch to a simple sugar; and
  • the role of enzymes, temperature, and concentration of reactants in the rate of a chemical reaction.

In addition, students should be able to

  • examine data to determine what factors have the greatest influence on the rate of a reaction, and
  • draw conclusions based on trends in experimental data.

National Science Education Standards
Unifying Concepts and Processes

  • Evidence, models, and explanations
  • Change, constancy, and measurement

Science as Inquiry

  • Abilities necessary to do scientific inquiry
  • Understandings about scientific inquiry

Physical Science

  • Chemical reactions

Science in Personal and Social Perspective

  • Science and technology in society

History and Nature of Science

  • Science as human endeavor
  • Nature of science
  • History of science

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Classroom activities are provided through the generous support of the Biogen Idec Foundation.